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. 2022 Jan 10;13:85. doi: 10.1038/s41467-021-27688-5

Fig. 1. Cryo-EM structures of ex vivo fibrils and of unseeded in vitro fibrils.

Fig. 1

Cryo-EM images and molecular models of ex vivo fibril morphologies I (orange) and II7,22 and of unseeded in vitro fibril morphologies i (light blue) and ii (purple). Scale bar of the cryo-EM images: 100 nm. The micrographs are representative for 1,429 micrographs of the ex vivo and 3,001 of the unseeded in vitro sample. The molecular models show one cross-sectional layer each and are based on the previously deposited PDB files for the ex vivo fibril morphology I (PDB 6DSO), ex vivo fibril morphology II (PDB 6ZCH), unseeded in vitro morphology i (PDB 6ZCF) and unseeded in vitro morphology ii (PDB 6ZCG)7,22.