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. 2022 Jan 10;13(1):35. doi: 10.1038/s41419-021-04491-0

Fig. 7. MiR-124-3p.1 enhances the curative efficacy of sorafenib in HCC in vivo.

Fig. 7

A Tumor regression rates were by tumor volume in nude mice (normal saline, sorafenib 10 µM, sorafenib 10 µM + miR-NC, sorafenib 10 µM + miR-124-3p.1 mimics; t-test). B Representative images of xenograft tumors in nude mice 2 weeks after different treatments. C TUNEL assay of cell apoptosis in the Hep3B tumors excised from nude mice after treatment (normal saline, sorafenib 10 µM, sorafenib 10 µM + miR-NC, sorafenib 10 µM + miR-124-3p.1 mimics; t-test). Data represent mean ± SD (n = ≥3 experiments). *P < 0.05, **P < 0.01, ***P < 0.001.