Table 1.
Overall study summary.
| Study duration (Days) | Cohort design animal numbers per group | Survival to term | Early deaths | |||
|---|---|---|---|---|---|---|
| Test | Surgical Control | Test | Control | Test | Control | |
| Cohort 3 30 ± 3 days | 4 | 1 | 4 | 1 | 0 | 0 |
| Cohort 2 90 ± 3 days | 5 | 1 | 3 | 1 |
1 @ D1 1 @ D12 |
0 |
| Cohort 1 365 ± 15 days | 3 | 1 | 2 | 1 | 1@D297 | 0 |
Study design matrix indicating study duration (cohort), numbers of animals per cohort and survival times for test (AD-MSC seeded scaffold implanted) and control animals (surgical esophagectomy with primary anastomosis).
D1 day 1, D12 day 12, D 297 day 297.