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. 2022 Jan 11;8:2. doi: 10.1038/s41421-021-00353-3

Fig. 8. The upregulation of APOE in HLA-DRhighFBP1high monocytes subsets and expansion of Treg in PBMCs of L-LEP patients.

Fig. 8

a Expression of APOE in HLA-DRhighFBP1high monocytes subsets of the discovery cohort. b ApoE protein concentration in the serum of L-LEP patients and HC (validation cohort 2) determined by ELISA. P value was calculated using a two-sided unpaired Student’s t test. c Percentage of Treg subset in T cells of the discovery cohort. P value was calculated using a two-sided unpaired Student’s t test. d Representative flow cytometry results for the determination of the percentage of Treg subset in CD3+ T cells. eg Percentage of CD4+ FOXP3+, CD4+ CD25+, and CD4+ CD25+ FOXP3+ Treg subset in CD3+ T cells of the validation cohort 2 determined by flow cytometry. P value was calculated using a two-sided unpaired Student’s t test. h The change in numbers of putative ligand-receptor pairs in PBMCs of L-LEP patients compared with HC indicated by dot plots (discovery cohort).