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. 2022 Jan 10;7:1. doi: 10.1038/s41541-021-00424-2

Fig. 2. Anti-hα-Syn antibodies induced by PV-1950 recognized LBs in the brains from DLB/AD cases and improve motor function of hα-Syn/Tg D line mice.

Fig. 2

a Representative images of the frontal cortex and amygdala sections from two DLB/AD cases stained with antibodies generated by PV-1950D and anti-αSyn commercial antibodies LB509. Magnification ×20, scale bar 50 μm. b Motor skills of female mice were tested in Fixed speed rotarod and accelerated speed rotarod. Statistical significance is calculated using an unpaired t-test. Due to high body weight and clumsiness, male mice were excluded from the behavior tests. Error bars indicate the mean values ± SEM.