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. 2022 Jan 10;7:1. doi: 10.1038/s41541-021-00424-2

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© The Author(s) 2022, corrected publication 2023

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Fig. 7 — a Representative images of brain sections from male mice immunostained with an antibody against the astroglial marker-GFAP. Each panel illustrates from top to bottom an overview of the brain, neocortex, hippocampus, striatum, and substantia nigra regions in non-Tg, and αSyn Tg mice with a vehicle, PV-1947D, PV-1948D, PV-1949D, and PV-1950D vaccination. b Image analysis of GFAP immunoreactivity expressed as corrected optical density in the neocortex, hippocampus, striatum, and substantia nigra of male mice. c Representative images of the brain sections of female mice immunostained with an antibody against the astroglial marker-GFAP. Each panel illustrates from top to bottom an overview of the brain, neocortex, hippocampus, striatum, and substantia nigra regions in non-Tg, and αSyn Tg mice with a vehicle, PV-1947D, PV-1948D, PV-1949D, and PV-1950D vaccination. d Image analysis of GFAP immunostaining expressed ad corrected optical density in the neocortex, hippocampus, striatum, and substantia nigra of female mice. The scale bar in the overview is 250 µm, the others are 25 µm. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.