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. 2022 Jan 30;28(1):145–158. doi: 10.5056/jnm21047

Table 2.

Clinical Characteristics of Non-overlap and Overlap Functional Gastrointestinal Disorders

Variables Healthy control (a)(n = 239) Non-overlap FGID (b) (n = 255) Overlap FGID (c) (n = 239) P-value Post-hoc
Age (yr) 55.1 ± 11.7 53.5 ± 13.5 49.4 ± 13.3 < 0.001 a > b, a > c
Females 146 (61.1) 132 (51.8) 152 (63.6) 0.019 a > b, b < c
Body mass index (kg/m2) 23.4 ± 3.4 23.2 ± 3.2 22.8 ± 3.2 0.139
Marriage 0.002 a < c, b < c
Single/divorced/widowed 32 (13.7) 29 (11.6) 54 (22.6)
Married 201 (86.3) 220 (88.4) 185 (77.4)
Education 0.125
Elementary/middle school 34 (16.3) 30 (14.7) 59 (28.9)
High school 44 (21.2) 115 (56.4) 35 (17.8)
University 130 (62.5) 63 (31.2) 103 (51.0)
Job 0.677
Employed 109 (52.9) 114 (56.4) 19 (9.4)
Unemployed 22 (10.7) 69 (34.2) 112 (55.2)
Housewives 75 (36.4) 14 (6.9) 77 (37.9)
Alcohol (> 35 g/wk) 29 (12.4) 31 (13.4) 32 (13.4) 0.939
Current smoker 11 (4.7) 34 (14.7) 35 (14.6) < 0.001 a < b, a < c
Daily spicy food ingestion 160 (77.7) 155 (72.1) 154 (74.0) 0.413
Anxiety HADS score 5.1 ± 3.5 5.2 ± 3.3 6.2 ± 3.7 0.012 a < c, b < c
Men 5.2 ± 3.0 5.1 ± 2.9 5.7 ± 2.9 0.614
Women 5.0 ± 3.9 5.3 ± 4.2 8.3 ± 4.1a 0.011 a < c, b < c
Depression HADS score 5.3 ± 3.5 5.5 ± 3.2 8.2 ± 3.6 < 0.001 a < c, b < c
Men 4.9 ± 2.7 5.5 ± 3.2 7.4 ± 3.2 0.007 a < c, b < c
Women 5.7 ± 4.1 5.6 ± 3.3 9.2 ± 3.9b 0.001 a < c, b < c

aP = 0.007 compared to men.

bP = 0.056 compared to men.

FGID, functional gastrointestinal disorder; HADS, hospital anxiety and depression scale.

Data are expressed as mean ± SD or n (%).