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. 2022 Jan 10;13:80. doi: 10.1038/s41467-021-27674-x

Fig. 3. Dynamics of cross-reactive T cells and RBD-specific antibody in PCR-positive and negative contacts.

Fig. 3

Serum sampled from COVID-19 contacts at the baseline, D7 and D28 visit were assayed for RBD-specific antibody, represented as sample/control ratios (a). PBMCs from these visits were rested overnight at high density prior to stimulation with 1 µg/ml cross-reactive peptide pool cultured for 20 h in a FLISpot assay to detect IL-2- (b) and IFNγ (c) secreting T cells. Serum from these visits were assayed for RBD-specific antibody, represented as sample/control ratios (c). Left-hand panels and blue circles represent PCR-negative contacts whilst right-hand panels and red circle represent PCR-positive contacts.