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. 2022 Jan 10;12:426. doi: 10.1038/s41598-021-04250-3

Table 4.

Comparison of the demographic and clinical characteristics of the participants (with migraine and probable migraine) presenting with visual aura in < 51% and > 51% of all headache attacks.

Migraine with visual aura in ≥ 51% of all headache attacks, N = 13 Migraine with visual aura in < 51% of all headache attacks, N = 37 P value PM with visual aura in ≥ 51% of all headache attacks, N = 15 PM with visual aura in < 51% of all headache attacks, N = 67 P value
Age (years) 38.0 (34.0–45.0) 41.0 (33.0–49.0) 0.595 37.0 (30.0–46.0) 45.0 (33.0–50.0) 0.117
Women 4 (30.8) 28 (75.7) 0.004 10 (66.7) 36 (53.7) 0.404
Frequency 2.0 (0.75–8.0) 4.0 (2.0–10.0) 0.719 4.0 (1.0–8.0) 2.0 (2.0–8.0) 0.555
HA days per month 2.0 (1.0–10.0) 5.0 (2.0–10.0) 0.282 3.0 (1.0–5.0) 2.0 (2.0–5.0) 0.336
Severe HA days per month 2.0 (1.0–5.0) 3.0 (1.0–5.5) 0.381 3.0 (1.0–5.0) 2.0 (1.0–3.0) 0.876
HA days with medication 1.0 (0.0–15.0) 3.0 (1.0–5.0) 0.518 2.0 (0.0–5.0) 2.0 (1.0–5.0) 0.615
Severe HA intensity 5 (38.5) 16 (43.2) 0.847 0 (0.0–0.0) 0 (0.0–0.0) 1.000
VAS score 7.0 (7.0–8.0) 7.0 (7.0–8.0) 0.655 7.0 (4.0–8.0) 6.0 (4.0–7.0) 0.455
HIT-6 score 50.0 (44.0–53.0) 54.0 (46.5–61.0) 0.545 46.0 (41.0–55.0) 50.0 (44.0–56.0) 0.328
MIDAS score 11.0 (6.0–41.5) 15.0 (9.0–15.0) 0.417 11.0 (5.0–47.0) 10.0 (5.0–24.0) 0.200
Unilateral pain 6 (46.2) 16 (43.2) 0.884 9 (60.0) 51 (76.1) 0.303
Pulsating pain 8 (61.5) 26 (70.3) 0.275 9 (60.0) 44 (65.7) 0.752
Aggravation by movement 11 (84.6) 29 (78.4) 0.215 12 (80.4) 44 (65.7) 0.268
Nausea 9 (69.2) 22 (59.5) 0.574 12 (80.0) 57 (85.1) 0.702
Vomiting 9 (69.2) 15 (40.4) 0.401 6 (40.0) 37 (55.2) 0.481
Photophobia 13 (100.0) 29 (78.4) 0.998 12 (80.0) 36 (53.7) 0.071
Phonophobia 9 (69.2) 22 (59.5) 0.121 11 (73.3) 42 (62.7) 0.567
WPI 3.0 (1.0–6.0) 6.0 (4.0–7.5) 0.559 7.0 (4.0–9.0) 4.0 (3.0–7.0) 0.028
PHQ-9 score 9.0 (7.5–10.5) 8.0 (6.0–9.0) 0.400 10.0 (8.0–18.0) 8.0 (6.0–9.0) 0.016
GAD-7 score 9.0 (4.5–10.5) 8.0 (3.0–13.0) 0.754 12.0 (5.0–15.0) 6.0 (4.0–9.0) 0.013
ASC-12 score 4.0 (2.5–8.0) 3.0 (0.5–8.0) 0.675 4.0 (2.0–8.0) 2.0 (0.0–6.0) 0.572
BEPSI-K score 3.0 (2.7–3.8) 2.6 (2.0–3.0) 0.045 3.2 (2.2–4.0) 2.2 (2.0–2.8) 0.006
M-TOQ-6 score 20.5 (15.3–22.8) 20.0 (16.5–24.3) 0.555 21.0 (18.0–26.0) 21.0 (17.0–25.0) 0.827
PSQI 9.0 (7.5–10.0) 7.0 (5.5–9.0) 0.130 10.0 (7.0–10.0) 7.0 (5.0–9.0) 0.032

PM: probable migraine, HA: headache, VAS: visual analogue scale, HIT-6: Headache Impact Test-6, MIDAS: Migraine Disability Assessment, WPI: Widespread Pain Index, PHQ-9: Patient Health Questionnaire-9, GAD-7: Generalized Anxiety Disorder-7, ASC-12: 12-item Allodynia symptom checklist, BEPSI-K: Korean version Brief Encounter Psychosocial Instrument, M-TOQ-6: 6-item version of the Migraine-Treatment Optimization Questionnaire, PSQI: Pittsburgh Sleep Quality Index.