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. 2022 Jan 10;12:443. doi: 10.1038/s41598-021-04167-x

Table 3.

Ocular surface evaluation in normal controls and MGD group.

Parameters Normal controls (n = 114) MGD group (n = 830) P-value
BCVA 0.9 ± 0.2 0.9 ± 0.2 0.451
IOP (mmHg) 14.0 ± 2.9 13.2 ± 2.5 0.078
OSDI 6.5 ± 4.8 26.0 ± 15.1 < 0.001*
TBUT (s) 7.3 ± 4.2 4.1 ± 2.3 0.002*
Schirmer I test (mm) 11.5 ± 9.4 10.1 ± 8.0 0.250
Lipid layer thickness (nm) 67.9 ± 21.9 51.7 ± 24.9 0.004*
Cornea staining 0.2 ± 0.6 0.7 ± 1.2 0.012*
MG loss (%) 11.5 ± 11.9 34.5 ± 12.2 0.002*
Rate of partial blinking 0.6 ± 0.3 0.6 ± 0.4 0.634
Lid margin abnormality score 1.2 ± 0.7 2.9 ± 0.8 0.002*
MG expressibility score 0.6 ± 0.1 1.7 ± 0.1 0.001*
Meibum score 0.5 ± 0.2 2.2 ± 0.2 0.010*

BCVA best-corrected visual acuity, IOP intraocular pressure, MGD meibomian gland dysfunction, TBUT tear film break-up time.

*P < 0.05 was considered statistically significant.