Table 3.
PORH | LD | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RF (PU) | BZ (PU) | PF (PU) | DF | HA (PU*sec) | HA index | Pre-heat LD | Post-heat LD | LD increase (%) | ||||||||||
Basal | ||||||||||||||||||
Control | 103.0 | [42.0–176.0] | 8.0 | [8.0–13.0] | 201.0 | [146.0–274.0] | 79.0 | [48.0–107.0] | 3015 | [1745–4108] | 27.9 | [10.0–77.3] | 122.0 | [38.0–179.0] | 232.0 | [132.0–278.0] | 118.0 | [20.0–219.5] |
Treated | 89.0 | [47.5–137.3] | 9.0 | [7.0–12.0] | 209.0 | [159.5–232.3] | 117.0 | [70.3–143.5] | 4336 | [2489–8194] | 49.4 | [20.6–133.7] | 84.0 | [50.0–123.0] | 210.0 | [187.3–278.0] | 244.3 | [71.9–397.1] |
3 months | ||||||||||||||||||
Control | 58.0 | [51.0–125.0] | 9.0 | [7.0–13.0] | 186.0 | [96– 222.0] | 99.0 | [51.0–148.0] | 4202 | [1283–6140] | 49.7 | [18.2–87.0] | 86.0 | [32.0–136.0] | 193.0 | [167.0–264.0] | 174.1* | [32.0–807.7] |
Treated | 74.5 | [53.8–104.3] | 9.5 | [6.5–11.5] | 201.5 | [164.8–224.0] | 124.5 | [71.3–157.0] | 4114 | [2328–8390] | 52.2 | [25.8–127.9] | 77.0 | [57.3–89.8] | 237.0 | [212.5–310.5] | 226.1* | [133.8–518.9] |
6 months | ||||||||||||||||||
Control | 41.0 | [21.0–70.0] | 7.0 | [6.0–15.0] | 116.0 | [82.0–189.0] | 63.0** | [53.0–78.0] | 2434 | [1766–3588] | 78.2 | [16.1–141.5] | 32.0 | [15.0–41.0] | 164.0 | [154.0–183.0] | 749.0* | [293.0–1196.0] |
Treated | 43.5 | [35.8–51.8] | 7.0 | [5.3–14.5] | 119.0 | [113.0–176.0] | 78.5** | [72.0–94.0] | 2814 | [1674–4350] | 72.0 | [32.5–114.5] | 40.5 | [33.3–56.8] | 191.5 | [163.0–211.8] | 400.0* | [232.5–415.8] |
PORH post-occlusive reactive hyperemia, LD laser Doppler, RF resting flow, BZ biological zero, PF peak flow, HA hyperemic area, PU perfusion unit.
DF = peak flow − resting flow.
Hyperemic area index = hyperemic area/resting flow.
*p < 0.05.
**p < 0.001.