Figure 1.

Histology and OCT optical property maps of the human somatosensory cortex. (a) Gallyas Silver stain shows contrast for myelin content. Red region: white matter. Green region: infragranular layers consist of layer IV, V and VI. Blue region: supragranular layers consist of layer I, II and III. Red arrow indicates a thin band of higher myelin content inside layer IV. (b) Optical density (OD) of Gallyas silver stain. The red arrow highlights the myelinated band inside the layer IV. (c,d) Nissl statin and COPA show contrast for cell bodies. The red region indicates the layer II and III with highest COPA value. The big black arrow highlights the high neuron density region. The small green arrows highlight the IV, V, VI layers within the infragranular layer with alternating contrasts. (e–g) Optical properties derived from the OCT images. (e) ${\mu }_s$ map. Small green arrows highlight the alternating contrasts in the infragranular layers similar to that in the COPA map, and the big red arrow indicates the myelinated band seen in Gallyas OD map. (f) ${\mu {}^{\prime }}_b$ map. Green arrow highlights the fibers with high intensity, possibly oriented within the imaging plane. (g) Ratio map of ${\mu {}^{\prime }}_b/{\mu }_s$ . Green arrow highlights the fibers with high intensity, similar to that in the ${\mu {}^{\prime }}_b$ map. The Blue arrow highlights the region with high signals in the supragranular layers. (h) OCT average intensity projection (AIP) image.