Table 1. Clinicopathological characteristics of the whole cohort (n=423).
| Variables | N=423 (%) |
|---|---|
| Age (years), median [ range] | 50 [22–75] |
| Menopausal status | |
| Premenopausal | 214 (50.6) |
| Postmenopausal | 209 (49.4) |
| Tumor histological grade | |
| 1 | 19 (4.5) |
| 2 | 176 (41.6) |
| 3 | 228 (53.9) |
| Subtypes | |
| Luminal | 125 (29.6) |
| HER2+ | 153 (36.1) |
| TNBC | 145 (34.3) |
| Histology | |
| Ductal | 373 (88.2) |
| Other | 39 (9.2) |
| Missing | 11 (2.6) |
| Lymphovascular invasion | |
| Present | 65 (15.4) |
| Absent | 358 (84.6) |
| Chemotherapy regimen | |
| Taxane ± Anthracycline | 355 (83.9) |
| Taxane ± Anthracycline + Vinorelbine | 65 (15.4) |
| Other | 3 (0.7) |
| Breast operation | |
| BCS | 103 (24.3) |
| Mastectomy | 320 (75.7) |
| Axillary staging methods | |
| SLNB | 131 (31.0) |
| ALND | 292 (69.0) |
| Clinical T category | |
| T1 | 52 (12.3) |
| T2 | 316 (74.7) |
| T3 | 41 (9.7) |
| T4 | 14 (3.3) |
| Clinical N category | |
| N0 | 148 (35.0) |
| N1 | 205 (48.5) |
| N2 | 63 (14.9) |
| N3 | 7 (1.6) |
| Post-treatment Pathological T category | |
| T0 | 76 (18.0) |
| Tis | 40 (9.5) |
| T1 | 207 (48.9) |
| T2 | 77 (18.2) |
| T3 | 17 (4.0) |
| T4 | 6 (1.4) |
| Post-treatment Pathological N category | |
| N0 | 249 (58.9) |
| N0(i+) | 6 (1.4) |
| N1mi | 7 (1.7) |
| N1 | 79 (18.7) |
| N2 | 54 (12.8) |
| N3 | 28 (6.6) |
| Clinical stage | |
| I | 20 (4.7) |
| II | 305 (72.1) |
| III | 98 (23.2) |
| Post-treatment pathological stage | |
| 0 | 101 (23.9) |
| I | 134 (31.7) |
| II | 103 (24.3) |
| III | 85 (20.1) |
| RCB class | |
| 0/pCR | 101 (23.9) |
| I | 74 (17.4) |
| II | 161 (38.1) |
| III | 87 (20.6) |
| Evaluation of Miller-Payne system | |
| G5 | 116 (27.4) |
| G4 | 88 (20.8) |
| G3 | 111 (26.2) |
| G2 | 37 (8.8) |
| G1 | 71 (16.8) |
HER2, human epidermal growth factor receptor 2; TNBC, triple negative breast cancer; BCS, breast-conserving surgery; SLNB, sentinel lymph node biopsy; ALND, axillary lymph node dissection; RCB, residual cancer burden; pCR, pathological complete response; G, grade.