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. 2021 Dec;10(12):3200–3210. doi: 10.21037/gs-21-545

Table 4. Multivariable cox regression analyses of survival in male thyroid cancer.

Characteristics Variable Cancer-specific survival Overall survival
HR (95% CI) P HR (95% CI) P
Tumor size ≤1 cm 1 1
>1 cm 3.354 (2.457–4.579) <0.001 0.984 (0.864–1.120) 0.802
Race Black 1 1
White 0.947 (0.596–1.505) 0.819 0.776 (0.630–0.955) 0.016
Other 0.933 (0.535–1.626) 0.807 0.742 (0.572–0.963) 0.025
Age, years <55 1 1
≥55 4.003 (3.161–5.070) <0.001 4.499 (3.967–5.102) <0.001
Median income <$55,000 1 1
≥$55,000 0.635 (0.493–0.816) <0.001 0.785 (0.687–0.897) <0.001
Surgery performed No 1 1
Yes 0.063 (0.045–0.088) <0.001 0.192 (0.152–0.242) <0.001
histology recode/pathological type Medullary 1 1
HCC 0.539 (0.348–0.836) 0.006 1.017 (0.737–1.403) 0.918
Follicular 0.247 (0.159–0.385) <0.001 0.814 (0.606–1.094) 0.173
Pap with Fv 0.107 (0.073–0.157) <0.001 0.719 (0.558–0.928) 0.011
Papillary 0.171 (0.126–0.231) <0.001 0.750 (0.592–0.951) 0.028
T stage Tx 1.912 (0.782–4.677) 0.156 0.677 (0.314–1.463) 0.321
T0 0.479 (0.177–1.296) 0.147 0.783 (0.462–1.326) 0.363
T1 0.036 (0.027–0.050) <0.001 0.391 (0.316–0.484) <0.001
T2 0.068 (0.048–0.095) <0.001 0.441 (0.351–0.554) <0.001
T3 0.154 (0.121–0.196) <0.001 0.498 (0.413–0.601) <0.001
T4 1 1
N stage Nx 0.642 (0.414–0.996) 0.048 1.214 (0.864–1.707) 0.263
N0 0.258 (0.225–0.296) <0.001 0.965 (0.822–1.133) 0.664
N1 1 1
M stage Mx 0.044 (0.024–0.081) <0.001 0.432 (0.260–0.718) 0.001
M0 0.024 (0.020–0.028) <0.001 0.364 (0.291–0.457) <0.001
M1 1 1
Combined summary stage Localized 1 1
Regional 3.688 (3.084–4.411) <0.001 1.135 (0.998–1.291) 0.054
Distant 56.280 (47.287–66.984) <0.001 2.153 (1.639–2.829) <0.001

HCC, Hurthle cell carcinoma; Pap with Fv, papillary with follicular variant.