Table 1. Review of the literature: MiNENs of pancreas.
| N | A | G | Tumor location | Diagnostic basis | Nonneuro/neuro component | Metastasis | Metastatic component | Surgery | Chem | Reference |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 63 | m | panc. head | Surgical specimen | n.a. adeno/G3 NEC | n | – | PD | y | (11) |
| 2 | 71 | m | panc. body | Surgical specimen | G3 adeno/G3 NET | n | – | DP | y | (11) |
| 3 | 73 | m | The ampulla of Vater | Surgical specimen | G2 adeno/G3 NET | n | – | PD | y | (11) |
| 4 | 77 | f | panc. body | Surgical specimen | G3 adeno/G1 NET | n | – | TP | y | (11) |
| 5 | 62 | m | panc. head | Surgical specimen | G2 adeno/G3 NET | n | – | PD | y | (11) |
| 6 | 64 | m | panc. head | Surgical specimen | G2 adeno/G3 NET | y#* | n.a. | PD | y | (11) |
| 7 | 82 | m | The ampulla of Vater | Surgical specimen | G2 adeno/G3 NEC | n | – | PD | n | (11) |
| 8 | 64 | f | panc. body | Surgical specimen | G2 acinar/G3 NEC | n | – | DP | y | (11) |
| 9 | 43 | m | panc. tail | Surgical specimen | n.a. acinar/G2 NET | y# | n.a. | DP & rHH | n | (11) |
| 10 | 30 | f | panc. tail | Surgical specimen | n.a. acinar/G2 NET | n | – | DP | y | (11) |
| 11 | 53 | m | panc. head | Surgical specimen | n.a. acinar/G2 NET | y#* | n.a. | PD | y | (11) |
| 12 | 56 | m | panc. head | Surgical specimen | IPMN/G2 NET | n | – | PD | n.a. | (12) |
| 13 | 81 | m | panc. head | Surgical specimen | G1–G2 adeno/G1 NET | n | – | PD | yes | (13) |
| 14 | 67 | f | panc. body | Surgical specimen | G1 adeno/G1 NET | n | – | PD | n.a. | (14) |
| 15 | 57 | m | The ampulla of Vater | Surgical specimen | G2 adeno/SCNEC | n | – | PD | n | (15) |
| 16 | 52 | m | panc. head | Surgical specimen | n.a. adeno/n.a. NEC | n | – | TP | n.a. | (16) |
| 17 | 33 | m | Uncinate process of the pancreas | EUS-FNA specimen | n.a. | y# | n.a. | Whipple procedure & hepatic mass resection | y | (17) |
| 18 | 66 | m | panc. tail | EUS-FNA specimen | G1 acinar/n.a. | y* | n.a. | n* | y | (17) |
| 19 | 60 | m | panc. head | EUS-FNA specimen | n.a. adeno/n.a. NEC | y#* | Neuro component | n* | y | (18) |
| 20 | 69 | m | The ampulla of Vater | Surgical specimen | G2 adeno/LCNEC | n | – | PD | n | (19) |
| 21 | 60 | m | The ampulla of Vater | EUS-FNA specimen | n.a. adeno/SCNEC | y* | n.a. | n* | n.a. | (19) |
| 22 | 57 | f | panc. body | Surgical specimen | acinar/n.a. | n | – | DP & S | y | (20) |
| 23 | 66 | m | Uncinate process of the pancreas | EUS-FNA specimen | acinar/n.a. | y# | Nonneuro & neuro component | n* | y | (21) |
| 24 | 63 | m | panc. head | Surgical specimen | G1–2 adeno/n.a. | y* | n.a. | PD | y | (22) |
| 25 | 43 | f | The ampulla of Vater | Surgical specimen | G3 adeno/n.a. | n | – | PD | y | (23) |
| 26 | 60 | f | The ampulla of Vater | Surgical specimen | G3 adeno/n.a. | n | – | PD | y | (23) |
| 27 | 78 | m | Uncinate process of the pancreas | EUS-FNA specimen | n.a./n.a. NET | y# | Neuro component | n* | y | (24) |
| 28 | 66 | m | panc. head | Surgical specimen | G1 adeno/SCNEC | y#* | Nonneuro or neuro component | PD | y | (25) |
N, number; A, age; G, sex; Chem, chemotherapy; f, female; m, male; EUS-FNA, endoscopic ultrasound-guided fine needle aspiration; n.a., information not available; adeno, adenocarcinoma; acinar, acinar carcinoma; NET, neuroendocrine tumor; NEC, neuroendocrine carcinoma; IPMN, intraductal papillary mucinous neoplasm; SCNEC, small cell neuroendocrine carcinoma; LCNEC, large cell neuroendocrine carcinoma; y*, lymph node metastasis; y#, liver metastasis; TP, total pancreatectomy; PD, pancreatoduodenectomy; DP, distal pancreatectomy; rHH, right hemihepatectomy; n*, not suitable for surgery or unresectable; S, splenectomy; y, yes; n, no.