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. 2021 Dec 6;13(4):355–363. doi: 10.34172/jcvtr.2021.53

Table 1. Baseline demographic, clinical, and laboratory characteristics of 196 patients with COVID-19.

Characteristics Total (n=196) Non-CV complication (n=142) CV complication (n=54) P -value
Age, median (IQR), y 65 (52-77) 65 (54.25-76.75) 65 (43.25-77.5) 0.713
Male, No. (%) 104 (53.1) 73 (51.4) 31 (57.4) 0.452
Comorbidities
Diabetes, No. (%) 34 (17.3) 22 (15.5) 12 (22.2) 0.266
Hypertension, No. (%) 105 (53.6) 79 (55.6) 26 (48.1) 0.348
Coronary artery disease, No. (%) 37 (18.9) 29 (20.4) 8 (14.8) 0.370
Heart failure, No. (%) 47 (24) 35 (24.6) 12 (22.2) 0.722
Chronic obstructive pulmonary disease, No. (%) 17 (8.7) 13 (9.2) 4 (7.4) 1
Cancer/autoimmune disease, No. (%) 13 (6.6) 12 (8.5) 1 (1.9) 0.118
Chronic kidney disease, No. (%) 7 (36) 5 (3.5) 2 (3.7) 1
Number of comorbidities
0 40 (20.4) 29 (20.4) 11 (20.4) 0.111
1 67 (34.2) 42 (29.6) 25 (46.3)
2 74 (37.8) 60 (42.3) 14 (25.9)
3 15 (7.7) 11 (7.7) 4 (7.4)
Clinical Presentation
Dyspnea, No. (%) 129 (65.8) 98 (69) 31 (57.4) 0.126
Chest pain, No. (%) 5 (2.6) 2 (1.4) 3 (5.6) 0.129
Fever, No. (%) 38 (23.8) 31 (25.4) 7 (18.4) 0.377
Systolic blood pressure, mean (SD), mmHg 117.5 (106.25-138) 115 (110-130) 120 (100-140) 0.519
Heart rate, median (IQR) 82 (76.25-100) 82 (78-99) 84 (72-100) 0.715
Respiratory rate, median (IQR) 20 (18-23.5) 20 (18-23) 20 (18-24) 0.982
Blood oxygen saturation, median (IQR), percent 93 (88-96) 93 (88-96.5) 93 (88-96) 0.771
Medication History
Aspirin, No. (%) 76 (38.8) 56 (39.4) 20 (37) 0.758
Atorvastatin, No. (%) 75 (38.3) 55 (38.7) 20 (37) 0.827
angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, No. (%) 74 (37.8) 56 (39.4) 18 (33.3) 0.431
Anticoagulant, No. (%) 23 (11.7) 15 (10.6) 8 (14.7) 0.409
Furosemide, No. (%) 32 (16.3) 24 (16.9) 8 (14.8) 0.724
Novel oral anticoagulant, No. (%) 4 (2) 3 (2.1) 1 (1.9) 1
Laboratory
Leukocytes, median (IQR), /μL 9800 (7450-13050) 9700 (6800-12525) 10100 (8000-13900) 0.150
Platelets, median (IQR), ×103/μL 208 (154-282) 212(154.5-277.2) 192 (153-310) 0.798
Erythrocyte sedimentation rate, median (IQR), percent 45 (25-82.75) 50 (22.5-82.5) 70 (38-100) 0.036*
Creatinine, median (IQR), mg/dL 1.2 (0.85-2) 1 (0.85-1.7) 1.3 (1-2) 0.181
Blood urea, median (IQR), mg/dL 27 (16-49.25) 25 (16-47) 34 (25-58) 0.065
Raised high-sensitivity Troponin I, No. (%) 27 (13.8) 5 (3.5) 22 (40.7) <0.001
C-reactive protein, median (IQR), mg/dL 70 (19-123.5) 71 (20.5-145) 140 (67-190) 0.041*
Raised N-terminal pro-B-type natriuretic peptide, No. (%) 141 (72) 96 (67.6) 45 (83.3) 0.029*
Procalcitonin, median (IQR), ng/mL 0.5 (0.1-2.7) 0.5 (0.1-3) 0.5 (0.18-3.5) 0.295
Interleukin-6, median (IQR), pg/mL 45 (14-126) 41 (14-120.5) 46 (13.5-148.25) 0.675

Abbreviation: IQR, interquartile range.