FIG 2.

Percentage of survival rates of the WT, ΔpckA, and COM strains in glycerol or acetate medium in response to treatment with isoniazid (INH) or bedaquiline (BDQ). CFU viability of the three strains after treatment with 0.3 μg/mL of INH (A and B) and BDQ (C and D) was calculated after a 5-day or 7-day incubation, respectively. The percentage of survival was calculated by the CFU at the final time point relative to input CFU. Three strains were cultured in medium containing glycerol (GLY [A and C]) or acetate (ACE [B and D]). All values are the average of experimental triplicates ± SEM and representative of at least two independent experiments. ***, P < 0.001 by Student’s unpaired t test.