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. 2022 Jan 10;5(1):e2143001. doi: 10.1001/jamanetworkopen.2021.43001

Table 2. Odds Ratios for the Association Between Race and Ethnicity and Therapeutic Inertia in the Systolic Blood Pressure Intervention Trial by Randomized Treatment Arm.

Variable % (95% CI)
Non-Hispanic White Non-Hispanic Black Hispanic
Standard arm
Unique participants, No. 2451 1306 384
Participant-visits, No. 13 726 7372 1746
Prevalence
Overalla 59.8 (58.9-60.7) 56.8 (54.4-59.2) 59.7 (56.5-63.0)
12 Mob 55.7 (51.3-60.1) 54.3 (48.0-60.4) 64.3 (51.2-75.5)
36 Mob 61.9 (55.3-68.1) 54.0 (44.8-62.9) 84.6 (70.3-92.8)
Adjusted odds ratio (N = 4092)b,c,d 1 [Reference] 0.85 (0.79-0.92) 1.00 (0.90-1.13)
Intensive arm
Unique participants, No. 2639 1329 447
Participant-visits, No. 22 319 10 716 2418
Prevalence
Overalla 56.0 (55.2-56.7) 54.5 (52.4-56.6) 51.0 (47.4-54.5)
12 Mob 54.8 (51.0-58.6) 51.4 (45.7-57.0) 35.5 (25.7-46.7)
36 Mob 67.0 (62.0-71.7) 66.7 (58.9-73.6) 50.0 (33.6-66.4)
Adjusted odds ratio (N = 4377)b,c,d 1 [Reference] 0.94 (0.88-1.01) 0.89 (0.79-1.00)
a

This is the estimated overall prevalence of therapeutic inertia among included participant-visits across time (1 to 48 months) accounting for within-patient correlation.

b

This is the observed prevalence of therapeutic inertia among visits at 12 or 36 months.

c

Sample sizes for individual models represent total unique participants in the model.

d

Results are shown for Model 3 which is adjusted for race/ethnicity, time, age, sex, education, employment, living with others, insurance status, source of care, smoking status, body mass index, depression, statin use, aspirin use, as well as systolic blood pressure, eGFR, serum potassium, serum sodium, number of antihypertensive medications, prior mTIS, ACEI/ARB, CCB, thiazide diuretic, loop diuretic, beta-blocker, alpha-blocker, number of non-antihypertensive medications, plus adjustment for serious adverse events reported within 1 month prior of the study visit.