Table 3.
Effects of dietary supplementation of synbiotics as a strategy to control Salmonella in poultry.
| Target Species | Synbiotic | Experimental Procedure | Main Results | Ref. |
|---|---|---|---|---|
| Hy-Line Brown laying hens | Commercial probiotic mix (Enterococcus faecium, Pediococcus acidilactici, Bifidobacterium animalis, Lactobacilus reuteri) + fructooligosaccharides | Symbiotic supplementation (20 g/1000 birds/day) of hens allocated on floor pens, orally-infected with S. Typhimurium PT 135 (106 CFU per bird), and vaccinated against Salmonella | The synbiotic enhanced the immune response in vaccinated hens, inhibiting Salmonella shedding pattern | [53] |
| Hy-Line pullets |
Commercial symbiotic: Bacillus + mannooligosaccharide | Pullets were supplemented with the symbiotic (0.075% w/w of diet formulated with 113 g/ton of amprolium) and challenged against a Nalidixic acid-resistant S. Enteritidis strain (3 × 106 CFU) | The symbiotic-supplemented birds exhibited reduced colonization of ceca and ovary with S. Enteritidis | [56] |
| Hy-Line W-36 laying hens |
Bacillus amyloliquefaciens, Bacillus licheniformis, and Bacillus pumilus (250 ppm) and yeast cell wall (mannan and β-glucan, 250 ppm) | Synbiotic were mixed with the commercial feed and supplemented to hens challenged against a nalidixic acid-resistant S. Enteritidis strain (7 × 107 CFU) | The synbiotic reduced the counts of S. Enteritidis from ceca | [48] |
| Dekalb White female chicks | Bacillus subtilis C-3102 (250,000 CFU/g) and 0.05% of yeast cell walls | Birds were allocated into floor cages and fed with a nonmedicated ration based on corn and soybean. A nalidixic acid-resistant strain of S. Enteritidis was inoculated to chicks (2.1 × 109 CFU) | A significantly lower abundance of Salmonella was found in the cecal microbiota of supplemented birds | [57] |
| Cobb broilers | Commercial synbiotic (Saccharomyces sp. and Lactobacillus sp.) | Birds feeding includes a commercial broiler feed supplemented with the commercial synbiotic. Broilers were allocated into battery cages and inoculated with S. Enteritidis (1 × 109 CFU) | Salmonella-challenged Broilers challenged, but synbiotic-supplemented increased the weight gain and maintained immunity response compared to its unsupplemented counterpart | [58] |
| COBB Avian48 broilers | Lactobacillus rhamnosus HN001 and Pediococcus acidilactici MA18/5M (7 log CFU, and fructans from Agave tequilana (4.5%) | Broilers were allocated into floor pens and fed with an antibiotic-free diet supplemented with the synbiotic. The challenge consisted of inoculation with S. Typhimurium PT 135 (105 log CFU per bird) | S. Typhimurium was inhibited in synbiotic-supplemented broilers and resulted in a decrease in the intensity and frequency of histopathological injuries | [55] |
CFU—colonies forming units.