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. 2021 Dec 20;87(1):693–707. doi: 10.1021/acs.joc.1c02699

Figure 1.

Figure 1

Typical reaction coordinates for two-step reactions with the first step as the rate-determining step (left) or the second (right) (top). Reaction coordinates for highly asynchronous concerted reactions taking place in one kinetic step but with two or more events featuring early (left) or late (right) transition states and the possibility of a hidden intermediate (bottom).