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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Cyclocreatine (cCr) IC50 values in PyMT ER-negative cells. IC50 values ± SEM were determined at 96 h, as described in the Materials and Methods section. IC50 values for independent experiments were calculated using non-linear regression and variable slope fit in Prism 9.0. Results from independent experiments were averaged to report the mean (n = 6, WT; n = 6, HIF-1 KO; n = 4, EV; n = 6, sh61).