Skip to main content
. 2021 Dec 22;14(1):27. doi: 10.3390/cancers14010027

Table 2.

Calculation of monotherapy IC50 values in human TNBC cell lines. IC50 values ± SEM were determined at 96 h, as described in the Materials and Methods. IC50 values for independent experiments were calculated using non-linear regression and variable slope fit in Prism 9.0. Results from independent experiments were averaged to report the mean (n = 4 replicates/cell line/drug).

Cell Line cCr
C50, mM
Taxol
C50, nM
DOX
C50, nM
MDA-MB-468 19.15 ± 3.06 11.16 nM ± 2.94 343.6 ±126.6
BT549 22.38 ±1.47 3.82 ± 0.44 28.28 ± 3.68
MDA-MB-453 6.10 ± 1.48 6.03 ± 1.75 60.39 ± 11.53