Figure 11.

Molecular docking of AgNPs determines the binding ability of silver with various bacterial and fungal proteins. A 3D structure modeling of the interaction of silver (gray ball in the center of each subdisplay (A–D)) with bacterial species: (A) Staphylococcus aureus, (B) Escherichia coli; and with fungal species: (C) Candida albicans, (D) Aspergillus flavus. AgNP interactions with microbes were achieved by hydrophobic contact. PDB IDs used included 3G7B (DNA gyrase, Staphylococcus aureus), 4WUB (DNA gyrase, Escherichia coli), 5TZI (cytochrome P450, Candida albicans), and 6DRS (dihydrofolate reductase, Aspergillus flavus).