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. 2021 Dec 27;14(1):106. doi: 10.3390/cancers14010106

Figure 6.

Figure 6

Functional affinities of three neoantigens: (a) MHC class I binding prediction values of 9-mer and 10-mer mCdt1 epitopes. (b) mCdt1-reactive CD8+ T cells were stimulated with 9-mer or 10-mer mCdt1 peptides at the indicated concentrations. IFN-γ production was evaluated by intracellular cytokine staining. (c) MHC class I binding prediction values of 8-mer, 9-mer, and 10-mer mScarb2 peptides. (d) mScarb2-reactive CD8+ T cells were stimulated with 8-mer, 9-mer, or 10-mer mScarb2 peptides at the indicated concentrations. IFN-γ production was evaluated by intracellular cytokine staining. (e) An IGV screenshot of the WES reads of the mZfp106 gene. (f) mZfp106-reactive CD8+ T cells were stimulated at the indicated concentrations with mZfp106 A656T&C659R, wild-type, A656T or C659R peptides. IFN-γ production was evaluated by intracellular cytokine staining.