Figure 3.

Fertility rate and fat content upon treatment with the four hit compounds. The treatment with the four compounds started from eggs on solid media. (a,d,g,j) Show the effect on fertility, expressed as eggs laid per animal per hour. (b,e,h,k) Show the effect of compounds on relative fertility, measured as the sum of total eggs laid in the entire fertile period, normalized on 100% of control. (c,f,i,l) Show the effect of compounds on fat content normalized on 100% of control (Mean Fluorescence Intensity, MFI). Measurements are indicated as mean ± SEM. One-way ANOVA. In all panels, asterisks (*) denote statistical significance, * p value ≤ 0.05, ** p value ≤ 0.01, *** p value ≤ 0.001, **** p value ≤ 0.0001 compared with control.