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Severe exacerbation rate according to prestudy treatment in (A) the pooled analysis of SYGMA (Symbicort Given as Needed in Mild Asthma) 1 and SYGMA 2 and (B) SYGMA 1. Subgroup 1 includes patients with asthma uncontrolled on as-needed short-acting bronchodilators alone. Subgroup 2 includes patients with asthma controlled on inhaled corticosteroids or leukotriene receptor antagonists. BUD = budesonide; CI = confidence interval; FORM = formoterol; RR = rate ratio.
