Table 1.
Blood and serum biochemistry parameters.
| Contents | Normal | HFHFD | CAE | MET | ||
|---|---|---|---|---|---|---|
| 100 | 200 | |||||
| Serum | AST (IU/L) | 51.0 ± 5.1 | 81.4 ± 13.4 ## | 65.3 ± 7.4 * | 62.4 ± 9.7 * | 71.0 ± 14.6 |
| ALT (IU/L) | 17.3 ± 3.0 | 48.2 ± 17.2 # | 31.6 ± 16.2 | 20.3 ± 4.9 * | 44.1 ± 31.7 | |
| TG (mg/dL) | 116.9 ± 11.4 | 137.4 ± 16.9 # | 140.7 ± 16.8 | 122.7 ± 8.4 * | 112.5 ± 10.8 ** | |
| TC (mg/dL) | 101.2 ± 5.6 | 180.9 ± 9.9 ## | 169.4 ± 18.6 | 148.6 ± 22.4 * | 162.5 ± 11.6 * | |
| LDL (mg/dL) | 15.8 ± 0.6 | 27.8 ± 2.6 ## | 22.7 ± 1.9 ** | 23.5 ± 1.2 ** | 26.3 ± 1.8 | |
| HDL (mg/dL) | 114.0 ± 14.3 | 72.5 ± 3.9 ## | 114.4 ± 9.3 ** | 124.2 ± 13.6 ** | 113.8 ± 6.2 ** | |
| FFA (mEq/L) | 0.89 ± 0.12 | 1.03 ± 0.01 # | 0.92 ± 0.04 ** | 0.85 ± 0.16 * | 0.97 ± 0.23 | |
| FBG (mg/dL) | 88.5 ± 7.4 | 163.2 ± 40.6 ## | 106.3 ± 10.9 * | 119.0 ± 18.8 * | 130.7 ± 16.8 * | |
#p < 0.05 and ## p < 0.01, as compared to normal group; * p < 0.05 and ** p < 0.01, as compared to the HFHFD group; HFHFD, high-fat and high-fructose diet; CAE, Cynanchum atratum extract; MET, metformin; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TG, triglyceride; TC, total cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; FFA, free fatty acid; FBG, fasting blood glucose.