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. 2021 Dec 30;11(1):124. doi: 10.3390/cells11010124

Figure 2.

Figure 2

IBA1+ cells are in intimate proximity with neurons. (a) Orthogonal projection and orthogonal dissections of PSD95+ post-synaptic material embedded within a pocket on the surface of an IBA1+ cell. (b) Instances of SYP+ presynaptic material embedded within a pocket on the soma of IBA1+ cell and partially internalised by process of the cell. (c) Orthogonal projection, with the XY, XZ and YZ planes showing PSD95+ material located within the IBA1+ cell. The white cut line crossing the IBA1+ cell on the XZ and XZ planes marks the Z-coordinate of the XY plane, while cut line areas drawn on the red-channel images overlay perimeter of the IBA1+ cell. Panels a and b come from organoids of the iPCS line MAD6, while panel c comes from MBE2968.