Table 3.

Prognostic models (Lasso Cox regression) of the 15 imaging features (Table S3) without and with clinical parameters (Table S2) combined, predicting locoregional recurrence-free survival, distant metastasis-free survival and overall survival (Table S8). The amount of features and the area under the curve (AUC) with the standard deviation (SD) is shown.

Cox Regression Models
Outcome	Features	Patients	Imaging Features			Clinical Parameters + Imaging Features
			Features	C index	SD	Features	C index	SD
Locoregional recurrence-free survival	PRE	57	15	0.70	0.18	22	0.69	0.15
	INTRA	57	15	0.48	0.10	22	0.48	0.10
	Delta	57	15	0.75	0.14	22	0.73	0.15
	ALL	57	45	0.72	0.15	52	0.72	0.16
Distant metastasis	PRE	57	15	0.79	0.13	22	0.75	0.15
	INTRA	57	15	0.64	0.16	22	0.64	0.14
	Delta	57	15	0.52	0.14	22	0.58	0.16
	ALL	57	45	0.77	0.14	52	0.75	0.14
Overall survival	PRE	57	15	0.65	0.18	22	0.75	0.15
	INTRA	57	15	0.48	0.12	22	0.55	0.14
	Delta	57	15	0.49	0.10	22	0.66	0.10
	ALL	57	45	0.53	0.16	52	0.62	0.15