Table 4.
The risk-of-locoregional-recurrence calculator, which can be used in clinical practice to calculate the risk per specific patient of locoregional recurrence during the follow-up time of 2 years. The yellow boxes can be filled in with the specific patient data in order to calculate the risk of locoregional recurrence, distant metastasis or death, in which gender is either 1 (male) or 0 (female). HPV status is either 1 (positive) or 0 (negative) and N-stage is either 0 (stage 0–1) or 1 (stage 2–3). The risk-of-metastasis calculator, which can be used in clinical practice to calculate the risk per specific patient of metastasis during the follow-up time of 2 years. The yellow boxes are filled in with the single patient data (with a large tumor) in order to calculate the risk of metastasis. The risk-of-death calculator, which can be used in clinical practice to calculate the risk per specific patient of death during the follow-up time of 2 years. The yellow boxes can be filled in with the single patient data in order to calculate the risk of death.
| Locoregional Recurrence Risk Calculator | Metastasis Risk Calculator | Death Risk Calculator | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Predictor | Fill-In | Formula | Result | Predictor | Fill-In | Formula | Result | Predictor | Fill-In | Formula | Result |
| PRE-ADC_kurtosis | x | 0.317326 | A | PRE-ADC_kurtosis | x | 1.233603 | A | Gender | x | −0.685436 | A |
| PRE-Kep | x | 0.168844 | B | PRE-SUV_peak | x | 0.167255 | B | HPV | x | −3.196345 | B |
| PRE-SUV_peak | x | 1.469971 | C | N-stage | x | 0.908168 | C | ||||
| Δ-ADC_skewness | x | 0.010764 | D | PRE-ADC_skewness | x | 0.925759 | D | ||||
| Δ-f | x | −0.036035 | E | PRE-D | x | −0.138775 | E | ||||
| Δ-SUV_peak | x | −0.190617 | F | PRE-f | x | −0.277885 | F | ||||
| Δ-TLG | x | −0.008579 | G | PRE-MATV | x | 8.640004 | G | ||||
| PRE-SUV_mean | x | −0.836001 | H | ||||||||
| PRE-SUV_peak | x | 1.885920 | I | ||||||||
| Linear probability | Y = −2.173498 + (Sum A + B + C + D + E + F + G) | Linear probability | Y = −5.950312 + (Sum A + B) | Linear probability | Y = −1.387043+ (Sum A + B + C + D + E + F + G + H + I) | ||||||
| Probability formula | 1/(1 + exp(−Y)) = | Probability formula | 1/(1 + exp(−Y)) = | Probability formula | 1/(1 + exp(−Y)) = | ||||||
| Risk | % | Risk | % | Risk | % | ||||||