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. 2021 Dec 31;11(1):103. doi: 10.3390/foods11010103

Table 1.

Concentration levels of main phenolic compounds in olive leaves.

Class Phenolic Compounds Range
(ng/mL Extract)
Ref Range
(mg/g dw)
Ref Range
(mg/g fw)
Ref
Secoiridoids Oleuropein aglycone 45.7–548.1 [8] 0.09–0.27 [48]
0.011–0.13 [8]
Oleuropein glucoside 380–1548 [8] 0.72–1.48 [48] 1.29–2.11 [49]
0.28–0.68 [50]
1.8–3.4 [49]
0.07–0.38 [8]
Demethyloleuropein 16.3–2121 [8] 0.18–0.40 [48]
0.0051–0.38 [8]
Oleuropein 50.4–23,485 [51] 15–81 [45] 30.46–71.12 [52]
6750–126,940 [4] 43.4–122.3 [53] 0.081–0.753 [54]
22,942 [55] 0.11–4.74 [56] 0.082–0.70 [57]
19,880–73,650 [53] 21.5–106.5 [58] 40.3–99.3 [59]
21,571–37,791 [8] 37.8–71.3 [48] 0.04–1.69 [60]
0.65–14.08 [50] 69–108.6 [49]
0.073–0.416 [61] 0.086–0.334 [61]
7.8–13.5 [62]
0.79–13.65 [4]
169.32–210.65 [63]
0.60–0.78 [64]
0.65–1.41 [65]
14.1–40.4 [66]
0.50–22.42 [60]
3–48 [49]
11.84–14.01 [67]
67.05–74.81 [68]
65.57–69.91 [69]
63.35 [30]
4.68–10.08 [8]
Hydroxyoleuropein 380.2–886.9 [8] 0.30–1.95 [50] 0.02–0.06 [60]
0.01–0.19 [60]
0.10–0.28 [8]
Ligstroside 0.78–0.99 [48] 1.18–4.16 [70]
0.36–0.95 [50] 0.01–0.11 [60]
0.01–0.80 [60] 1.35–2.13 [49]
0.6–0.9 [49]
Methoxyoleuropein 0.051–0.186 [48]
Oleoside 0.031–0.051 [48] 0.05–0.08 [60]
0.97–2.22 [50]
0.10–0.15 [60]
Secologanoside 0.92–1.49 [48] 0.28–0.37 [60]
0.18–0.81 [60]
Verbascoside 914 [55] 0.62–2.23 [53] 0.47–1.26 [52]
2.9–26 [8] 0.005–0.170 [56] 0.021–0.148 [54]
2.91 [71] 0.36–2.31 [72]
0.178–0.351 [62] 0.01–0.18 [60]
1.98–4.40 [66] 1.5–2.7 [49]
0.06–1.05 [60]
0.3–1.9 [49]
0.43–0.47 [68]
0.060–2.32 [8]
Isoverbascoside 91.6–3847 [8] 0.024–0.97 [8]
Elenolic acid glucoside 0.111–0.536 [48]
0.52–4.03 [50]
Flavonoids Flavones
Luteolin 71.5–2357 [51] 0.09–3.04 [45] 0.003–0.400 [54]
0.0018–0.274 [56] 0.14–0.58 [60]
0.006–0.025 [48]
0.220 [71]
0.14–0.63 [66]
0.05–1.18 [60]
0.07–0.60 [73]
Luteolin-7-O-glucoside 2370–9030 [4] 0.94–4.65 [53] 0.31–1.54 [60]
3742 [55] 0.0083–0.819 [56] 8.9–10.6 [49]
197.7–658.1 [8] 2.25 [71]
0.28–0.97 [4]
0.49–0.83 [64]
0.76–1.30 [65]
2.95–4.45 [66]
1.02–2.15 [60]
2.6–11.1 [49]
1.32–1.82 [69]
2.71 [30]
0.05–0.12 [8]
Luteolin glucoside 1.53–2.62 [48] 0.18–0.73 [60]
0.60–1.54 [50]
0.32–0.90 [60]
Luteolin diglucoside 12.4–104.8 [8] 0.15–0.25 [48] 0.01–0.03 [60]
0.02–0.05 [60]
0.003–0.03 [8]
Luteolin rutinoside 0.19–0.41 [48] 0.02–0.11 [60]
0.14–0.22 [60] 0.91–1.14 [49]
0.48–0.99 [49]
Luteolin-4′-O-glucoside 0.234–0.493 [62]
0.22–0.30 [64]
0.25–0.31 [65]
19.16–31.02 [73]
Apigenin 31.9–198 [51] 0.093 [71]
0.023–0.094 [66]
0.038 [73]
Apigenin-7-O-glucoside 2147 [55] 0.73–3.01 [53] 0.013–1.46 [57]
0.0094 –2.476 [56]
0.347 [71]
0.28–0.85 [66]
1.00–2.06 [73]
Apigenin diglucoside 11.2–31.6 [8] 0.09–0.26 [49] 0.12 [49]
0.0028–0.0081 [8]
Apigenin rutinoside 4.9–81.1 [8] 0.033–0.061 [48] 0.10–0.13 [60]
0.14–0.31 [64] 0.74 [49]
0.25–0.39 [65]
0.06–0.17 [60]
0.33–0.66 [49]
0.0012–0.013 [8]
Diosmetin 14.5–159 [51]
Chrysoeriol-7-O-glucoside 0.058–0.173 [48]
Flavanones
Eriodictyol 0.0068 [71]
Hesperidin 0.304 [71]
Naringenin 0.029–4.05 [57]
Neohesperidin 0.39–0.99 [49] 0.78–1.13 [49]
Flavonols
Rutin 357 [55] 0.02–1.65 [45] 0.034–1.331 [54]
0.0026–0.825 [56] 0.03–0.14 [60]
0.18–0.29 [48]
0.35–0.98 [66]
0.19–0.39 [60]
2.01–2.94 [68]
0.43–0.85 [73]
Quercetin rutinoside 14.89 [55] 0.078–0.245 [64]
191–1379 [8] 0.16–0.25 [65]
0.047–0.37 [8]
Quercetin galactoside 30.57 [55]
Quercetin glucoside 0–115.3 [8] 0–0.003 [8]
Quercetin rhamnoside 0–86.9 [8] 0–0.0023 [8]
Quercetin 0.021–247 [51] 0.02–0.37 [45] 0.002–2.73 [57]
0.18–0.76 [53]
0.040 [71]
0.0008–0.0021 [73]
Hyperoside 0.067 [71]
Kaempferol 0.0029 [71] 0.039–8.86 [57]
Isorhamnetin 0.052–2.41 [57]
Flavanonols
Taxifolin 0.0082 [71]
Flavan-3-ols
Catechin 0.18–0.36 [66]
0–0.0376 [56] 0.16–3.29 [57]
Epicatechin 21.7 [55]
Simple Phenylethanoids
phenols Tyrosol 1681 [55] 0.2–1.95 [45] 0.001–0.036 [54]
0.0021–0.175 [56]
0.033–0.088 [66]
Tyrosol glucoside 0.76–1.44 [48]
Hydroxytyrosol 9.2–3682 [51] 0.02–27.20 [45] 0.189–1.313 [54]
10,925 [55] 0.0054 –0.290 [56]
0.56–2.94 [58]
0.21–0.60 [66]
0.33–0.40 [67]
0.87–2.19 [68]
Hydroxytyrosol glucoside 570–2357 [8] 1.61–2.37 [48] 1.01–4.60 [52]
0.57–1.41 [60] 0.85–3.41 [72]
0.13–0.58 [8] 0.82–1.03 [60]
Hydroxycinnamic acids
Caffeic acid 201.5 [55] 0.34–2.11 [45] 0.014–0.85 [57]
0.0026–0.432 [56] 0.04–0.10 [72]
0.015 [71]
0.27–0.39 [68]
p-Coumaric acid 0.81 [55] 0.15–2.34 [45] 0.003–0.49 [57]
0.081 [71]
Chlorogenic acid 30.72 [55] 0.0027 [71]
0.39–0.47 [68]
Cinnamic acid 0.005–1.09 [57]
Ferulic acid 0.003–0.25 [45] 0.016–0.79 [57]
0.046 [71]
Syringic acid 0.002–0.09 [45] 0.017–1.16 [57]
0.0028 [71]
hydroxybenzoic acids
Vanillic acid 0.0032–0.257 [56]
0.016 [71]
Vanillin 0.47 [55] 0.0016–0.147 [56]
Sinapic acid 0.0049 [71]
Gallic acid 1.73 [55] 1.15–3.04 [45] 0.68–1.45 [57]
0.0026 [71]
Protocatechuic acid 0.40–3.23 [45]
17.48 [71]
2,5-Dihydroxybenzoic acid 0.0055 [71]
3,4-Dihydroxybenzoic acid 0.11–2.07 [57]
4-Hydroxybenzoic acid 0.015 [71]
3,4-Dihydroxyphenylacetic acid 0.47 [71]
Lignans Pinoresinol 0.004 [71]

Dw: dry weight; fw: fresh weight.