Table A1.
Scoring of muscle pathology at standard staining.
| Diagnosis | VAS-Score | HE | COX-SDH | ALP | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Perifascicular Atrophy (PA) | Punched-Out-Vacuoles (POV) | Necrosis | Regeneration | Oedema | Inflammation | COX-Negative Fibers | Upregulation | |||
| P1 | DM | 4 | 1 | 0 | 1 | 2 | 1 | 1 | 2 | 0 |
| P2 | DM | 6 | 3 | 1 | 0 | 3 | 1 | 1 | 3 | 0 |
| P5 | DM | 6 | 1 | 3 | 1 | 1 | 3 | 2 | 3 | 0 |
| P10 | DM | 4 | 0.5 | 0 | 1 | 1 | 1 | 0.5 | 0 | 0 |
| P11 | DM | 1 | 0 | 0 | 0 | 0 | 0 | 0.5 | 0 | 0 |
| P12 | DM | 8 | 3 | 1 | 2 | 3 | 2 | 2 | 3 | 0 |
| P15 | DM | 2 | 0 | 0 | 1 | 0.5 | 1 | 0.5 | 0 | 0 |
| P4 | DM (NXP-2) |
9 | 3 | 3 | 1 | 3 | 2 | 1 | 3 | 0 |
| P13 | DM (NXP-2) |
1 | 0 | 0 | 0 | 0 | 0 | 0.5 | 0 | 0 |
| P8 | ASyS (Jo-1) |
4 | 1 | 0 | 2 | 1 | 1 | 1 | 0 | 1 |
| P14 | ASyS (Jo-1) |
9 | 3 | 3 | 3 | 3 | 3 | 2 | 0 | 2 |
| P6 | ASyS (PL-7) |
2 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
| P9 | ASyS (PL-7) |
2 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
| P3 | OM (SLE) |
4 | 1 | 0 | 2 | 2 | 0 | 1 | 0 | 0 |
| P7 | OM (SLE) |
6 | 0 | 0 | 2 | 2 | 1 | 2 | 0 | 0 |
DM = dermatomyositis; ASyS = antisynthetase syndrome; OM = overlap myositis; SLE = systemic lupus erythematosus.