Table 1.
Effect of hidrosmin on metabolic parameters in diabetic mice. Abbreviations: KBWR, kidney–body weight ratio; GLU, glucose; BUN, blood urea nitrogen; ASAT, aspartate aminotransferase; ALAT, alanine aminotransferase; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. Values are mean ± SEM of the total number of animals per group (n = 9–11). * p < 0.05 and ** p < 0.01 vs. diabetic group.
| Metabolic Parameters | Diabetic | Diabetic + Hidrosmin |
|---|---|---|
| Body Weight (g) | 22.1 ± 0.7 | 21.9 ± 0.8 |
| KBWR (g/g) | 9.8 ± 0.7 | 9 ± 0.4 |
| GLU (mg/dL) | 484.8 ± 22.7 | 420.3 ± 41,4 |
| Water intake (mL/day) | 30 ± 3.4 | 28.9 ± 3.1 |
| Urea (mg/dL) | 70.1 ± 6.8 | 64.5 ± 4.2 |
| BUN (mg/dL) | 32.8 ± 3.2 | 30.1 ± 2 |
| ASAT (UI/L) | 212 ± 28.8 | 197.1 ± 60.1 |
| ALAT (UI/L) | 79.1 ± 13.7 | 93.8 ± 15.5 |
| TC (mg/dL) | 911.7 ± 74.5 | 573.3 ± 83.9 ** |
| TG (mg/dL) | 228.7 ± 47 | 140.6 ± 21.2 |
| HDL-C (mg/dL) | 92.2 ± 6.7 | 79.4 ± 5.1 |
| LDL-C (mg/dL) | 750.9 ± 61.6 | 513.1 ± 71.2 * |