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Human PCa model diagram. Cells are represented in orange squared boxes, while molecules in green rounded ones. The Castration-Resistant Prostate Cancer (CRPC) has been highlighted by a blue box. Other players involved: Dendritic cells (D), regulatory T cells (Treg), Cytotoxic T Lymphocytes (CTL), Interleukin-2 (IL-2) and ipilimumab (). The lines represent promotions and inhibitions, while dashed lines depict the treatments: dendritic cell vaccine (V) and anti-CTLA4 drug (AC).
