Table 5.
Morphometric variables from aortic sections (mean ± standard deviation) of nondiabetic rats (NDR), diabetic control rats (DR), and DR treated with hydroxytyrosol (HT) 5 mg/kg/day p.o. (HT-5), 3′,4′-dihidroxifenilglicol (DHPG) 0.5 or 1 mg/kg/day p.o. (DHPG-0.5, DHPG-1), or their association. n = 10 rats per group.
Variable | NDR | DR | HT-5 | DHPG-0.5 | DHPG-1 | HT-5 + DHPG-0.5 | HT-5 + DHPG-1 |
---|---|---|---|---|---|---|---|
Aortic thickness (µm) | 108 ± 5.8 | 144 ± 5.2 (+) | 113 ± 7.9 (*) | 120 ± 3.3 (*) | 190 ± 9.4 | 117 ± 4.2 (*) | 118 ± 4.8 (*) |
Smooth muscle cells (n/105 µm2) | 41.9 ± 2.2 | 55.2 ± 2.8 (+) | 44.5 ± 3.5 (*) | 41.2 ± 2.1 (*) | 41.3 ± 1.9 (*) | 38.1 ± 3.8 (*) | 44.0 ± 1.9 (*) |
+p < 0.05 with respect to NDR; * p < 0.05 with respect to DR.