Table 3.
Altered Functional Modules in MDMs (Compared With Early EPCs)
| Biological Process | Count | % | p |
|---|---|---|---|
| Negative regulation of gene expression | 8 | 10.96 | 0.0033 |
| Response to organic substance | 9 | 12.33 | 0.0066 |
| Negative regulation of macromolecule metabolic process | 9 | 12.33 | 0.0073 |
| Negative regulation of transcription | 7 | 9.590 | 0.0088 |
| Cortical actin cytoskeleton organization* | 3 | 3.371 | 0.0122 |
| Negative regulation of nucleobase and nucleic acid metabolic process | 7 | 9.590 | 0.0145 |
| Negative regulation of nitrogen compound metabolic process | 7 | 9.589 | 0.0154 |
| Negative regulation of macromolecule biosynthetic process | 7 | 9.589 | 0.0195 |
| Negative regulation of cellular biosynthetic process | 7 | 9.589 | 0.0218 |
| Negative regulation of biosynthetic process | 7 | 9.589 | 0.0239 |
| Cell proliferation | 6 | 8.219 | 0.0275 |
| Blood circulation | 4 | 5.479 | 0.0363 |
| Steroid metabolic process | 4 | 5.479 | 0.0446 |
| Response to inorganic substance | 4 | 5.479 | 0.0462 |
| Posttranscriptional regulation of gene expression | 4 | 5.479 | 0.0496 |
| Positive regulation of TGFB receptor signaling pathway | 2 | 2.741 | 0.0498 |
*
Discussed in the text.