Table 5.

AA Diffusion coefficients in PLA films obtained using different processing techniques.

Active Agent	Processing Technique	Release Conditions	Diffusion Coefficient (m2 s−1)	References
Merkén	Extrusion	EtOH 50% at 40 °C	2.0 × 10−13	[43]
Thymol	Extrusion	EtOH 95% at 40 °C	6.0 × 10−13	[12]
	Solvent Casting	EtOH 10% at 40 °C	2.5 × 10−13	[46]
	Supercritical impregnation	EtOH 10% at 40 °C	1.5 × 10−13	[15]
		EtOH 95% at 40 °C	2.8 × 10−11
Cinnamaldehyde	Electrospinning	EtOH 50% at 40 °C	1.0 × 10−12	[42]
	Supercriticalimpregnation		6.0 × 10−14
	Casting (PLA monolayer)	EtOH 50% at 20°C	6.3 × 10−14	[79]
	Thermo-compression (PLA-bilayer)		9.0 × 10−15