Figure 1.

AG490 improved cerebral ischemia injury: (A) neurological deficits after permanent cerebral ischemia for 24 h in sham and stroke rats receiving normal saline or AG490 (5 mg/kg); (B) average infarction volume of ipsilateral hemisphere by TTC staining; (C) water contents in the ipsilateral cortical tissues; (D) caspase-3 activity by an enzymatic assay in the ipsilateral cortical tissues; and (E) Western blot of the ipsilateral cortical tissue proteins with the indicated antibodies and the quantitative results. * p < 0.05 vs. sham/saline; ^# p < 0.05 vs. ischemia/saline, n = 8.