Table 1.
Samples | Cytokines (pg/mg) |
Standard Environment |
Enriched Environment |
---|---|---|---|
Plasma | IL-15 | 226.5 ± 49.4 a | 1.00 × 10−4 ± 1.00 × 10−4 b |
LIF | 6.36 ± 2.47 a | 1.00 × 10−4 ± 1.00 × 10−4 b | |
CX3CL1 | 1448 ± 404 | 1081 ± 253 | |
Tumour | IL-15 | 0.28 ± 0.19 a | 1.00 × 10−4 ± 1.00 × 10−4 b |
LIF | 0.63 ± 0.17 | 0.67 ± 0.15 | |
CX3CL1 | 0.78 ± 0.04 a | 0.55 ± 0.03 b | |
Contralateral mammary gland | IL-15 | 0.17 ± 0.17 a | 1.00 × 10−4 ± 1.00 × 10−4 b |
LIF | 0.002 ± 0.001 a | 1.00 × 10−4 ± 1.00 × 10−4 b | |
CX3CL1 | 0.42 ± 0.12 a | 0.34 ± 0.05 b | |
Gastrocnemius | IL-15 | 1.294 ± 0.25 a | 0.32 ± 0.64 b |
LIF | 6.6× 10−3 ± 1.2 × 10−3 a | 1.00 × 10−4 ± 1.00 × 10−4 b | |
CX3CL1 | 0.66 ± 0.04 a | 0.42 ± 0.14 b | |
Inguinal adipose tissue | IL-15 | 0.39 ± 0.15 a | 1.00 × 10−4 ± 1.00 × 10−4 b |
LIF | 0.020 ± 0.015 a | 1.00 × 10−4 ± 1.00 × 10−4 b | |
CX3CL1 | 0.82 ± 0.22 a | 0.43 ± 0.11 b |
Results are in pg/mg of proteins and mean ± SEM (n = 5 mice tissue or plasma samples/group). Data were analysed by two-way ANOVA for tumour-bearing mice housed in standard environment vs. tumour-bearing mice housed in enriched environment. Representative data are shown for a, b, and unlabelled (nonsignificant difference, p < 0.05).