Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Major ROS sources in melanocytes. ROS can be generated from UV irradiation, melanosomes, mitochondria, and NOS and NOX family enzymes. Moreover, NOX enzymes can be activated by arachidonic acid metabolites from both the COX and LOX pathways, as well as from the activated N-RAS, AKT, and RAC1 oncogenic pathways.
