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. 2021 Dec 22;14(1):32. doi: 10.3390/cancers14010032

Table 3.

Cytogenetic characteristics of B-ALL patients with <40 chromosomes.

Age (Years) Near-Haploid Low-Hypodiploid Reference
MN Retained chr Lost chr Doubled Clone Frequency MN Retained chr Lost chr Doubled Clone Frequency
1–18 25–28 8, 10, 14, 18, 21 and sex chr. yes 0.0046 30–40 1, 19, 21, 22 and sex chr. 3, 7, 13, 16, 17 yes 0.41 [17]
1–10 24–28 8, 10, 14, 18, 21 and sex chr. 7, 13, 14, 20, X yes 0.0042 33–44 7, 13, 14, 20, X nr 0.79 [19]
2–15 23–29 14, 18, 21 and sex chr. yes 0.0039 33–39 1, 2, 5, 6, 8, 10, 11,12, 14, 18, 19, 21, 22 and the sex chr. 7, 17 yes 0.39 [21]
15–84 - - - - - 30–39 1, 5, 6, 8, 10, 11, 15, 18, 19, 21, 22, X, Y 3, 7, 15, 16, 17 66 to 78 chr 0.05 [31]
15–55 - - - - - 33–39 nr nr nr 0.0008 [21]
15–55/>55 <30 0.0016 32–39 1 2, 3, 7, 9, 13, 15, 16, 17, 20, 4 64–74 3.85% [40]
1–9/>10 24–29 14, 18, 21 and sex chr. nr nr nr 33–39 nrec 3, 7, 16, 17 nr nr [10]
<31 24–31 14, 18, 21 and sex chr. nr yes 0.008 32–39 1, 8, 10, 11, 18, 19, 21 and 22 nr nr 0.0064 [41]

Abbreviations: chr, chromosomes; MN, modal numbers; nr, non-reported; nrec, non-recurrent.