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. 2021 Dec 26;14(1):100. doi: 10.3390/cancers14010100

Figure 4.

Figure 4

EC Classification: (A) EC1 is considered as non-neoplastic, with regularly arranged glands, well-preserved lumen, and poorly stained nuclei; (B) EC2 is considered as adenoma, with a more compact glandular arrangement, lumen narrowing and poorly stained nuclei; and (C) EC3 is considered as carcinoma with distorted glandular structure and enlarged nuclear sign. The border between the background mucosa and the cancerous area can be noted in this photo.