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. 2021 Dec 26;14(1):100. doi: 10.3390/cancers14010100

Table 4.

Gastric EC Classification.

Characteristics EC1 EC2 EC3
Glandular pattern Regularly arranged glands with consistent pattern Recognizable glandular structure with more compact arrangement Distortion and loss of glandular structure
Lumen Well-preserved lumen Lumen narrowing (Slit-like) No recognizable lumen
Nuclei Uniform pattern of small, round, poorly stained nuclei with homogenous size Small, round, poorly stained nuclei with pseudostratification Hyperchromatic, disarranged nuclei with heterogeneity in size and shape, significant swelling of the nuclei = “enlarged nuclear sign”
Expected Histology Non-neoplastic Adenoma Carcinoma

EC: endocytoscopy.