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. 2021 Dec 21;11(1):4. doi: 10.3390/cells11010004

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Body and fat-pad weights of Ppara^FatKO and Ppara^fl/fl mice fed high-fat or normal-chow diets. Male (A) and female (B) Ppara^FatKO and Ppara^fl/fl mice were placed on high-fat (HFD) or normal-chow (NCD) diets for 30 weeks and body weights, total fat, inguinal white adipose tissue (iWAT), epididymal white adipose tissue (eWAT), and brown adipose tissue (BAT) were measured at the end of the study. ** p < 0.01, two-way ANOVA (vs. Ppara^fl/fl HFD) (± S.E.M.; male n = 11 NCD and n = 9 HFD, Ppara^fl/fl; female n = 13 NCD and n = 6 HFD, Ppara^fl/fl; male n = 13 NCD and n = 14 HFD, Ppara^HepKO; female n = 14 NCD and n = 6 HFD, Ppara^HepKO).