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. 2021 Dec 21;11(1):4. doi: 10.3390/cells11010004

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Lipidomics of iWAT in Ppara^fl/fl and Ppara^FatKO mice. Lipidomics of iWAT using liquid chromatography–mass spectrophotometry (LC mass spec) represented as volcano-plot analysis in male (A) and female (B) Ppara^FatKO and Ppara^fl/fl mice on high-fat (HFD) or normal-chow (NCD) diets. Organization of the top 50 and bottom 50 most-changed lipids in male (C,D) and female (E,F) Ppara^FatKO and Ppara^fl/fl mice. The blue arrows identify cholesterol esters. (male n = 7 NCD and n = 8 HFD, Ppara^fl/fl; female n = 6 NCD and n = 4 HFD, Ppara^fl/fl; male n = 7 NCD and n = 8 HFD, Ppara^HepKO; female n = 6 NCD and n = 4 HFD, Ppara^HepKO).