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[Preprint]. 2022 Jan 26:2022.01.03.474779. Originally published 2022 Jan 4. [Version 3] doi: 10.1101/2022.01.03.474779

PMC8750650.1; 2022 Jan 4
PMC8750650.3; 2022 Jan 26

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Figure 6. — Effect of CSNK2A inhibition on His6-SARS-CoV-2 spike protein uptake into HEK293T-ACE2 cells. (A) Cell nuclei stained with DAPI. Spike protein detected using a His6 antibody, Cells were treated with 1 μM of CSNK2A inhibitors (SGC-CK2–1 or Compound 2), negative control (SGC-CK2–1N), or vehicle control (DMSO). (B) Quantification of the His6-SARS-CoV-2 spike protein uptake. The data is from 3 separate experiments with n = 9 for each sample. The total spike-His tag fluorescence was divided by the number of cells to control for the number of cells per frame. AU, arbitrary units; ns, not significant; **** p < 0.0001.