Table 2.
Intensity average hydrodynamic diameter and corresponding PdI, determined by DLS, ζ-potential value, and drug encapsulation efficiency (EE%) of all prepared micelles.
| Micelles Samples | dmean | PdI | ζ-Potential | EE% | |||
|---|---|---|---|---|---|---|---|
| pH 7.4 | pH 6.8 | pH 7.4 | pH 6.8 | pH 7.4 | pH 6.8 | ||
| NoResMic | 102.70 ± 5.64 | 92.24 ± 4.54 | 0.16 ± 0.02 | 0.14 ± 0.05 | 16.60 ± 4.53 | 20.60 ± 3.32 | / |
| pHResMic | 90.20 ± 1.26 | 86.47 ± 1.22 | 0.18 ± 0.03 | 0.15 ± 0.05 | −19.30 ± 3.33 | 25.50 ± 1.59 | / |
| TpHResMic | 165.60 ± 1.24 | 130.60 ± 1.08 | 0.23 ± 0.01 | 0.26 ± 0.02 | −15.64 ± 0.86 | 13.70 ± 1.87 | / |
| Gem@pHResMic | 92.10 ± 1.12 | 104.30 ± 1.23 | 0.15 ± 0.02 | 0.16 ± 0.04 | −15.20 ± 2.09 | 22.80 ± 1.50 | 22.00% ± 2.10 |
| Gem@TpHResMic | 134.30 ± 3.74 | 124.40 ± 3.47 | 0.22 ± 0.05 | 0.19 ± 0.05 | −13.80 ± 1.69 | 16.80 ± 0.70 | 29.00% ± 1.22 |