Figure 2. Emergence of bamlanivimab resistance mutations correlates with recrudescent shedding of culturable virus.

(A) Viral load and culture positivity at baseline and day 1 post-treatment for four study participants with recrudescent shedding of culturable virus. Cx, culture (B-E) Viral load and TCID₅₀ for four study participants whose infecting virus developed E484 mutations of the spike protein following bamlanivimab monotherapy.