AD |
Alzheimer’s disease |
ADP |
Adenosine diphosphate |
AGEs |
advanced glycation end products |
AMPK |
5’-adenosine monophosphate (AMP)-activated protein kinase |
APAF1 |
Apoptotic peptidase-activating factor 1 |
ATP |
Adenosine triphosphate |
ATP13A2 |
Atpase type 13 a 2 |
BAK |
Bcl2-antagonist/killer |
BAX |
Bcl-2-associated x protein |
Ca2+
|
Calcium |
CoQ |
Co-enzyme q |
CR |
Caloric restriction |
CVD |
Cardiovascular diseases |
DJ-1 |
Daisuke-junko-1 |
DPP-4 |
dipeptidyl peptidase-4 |
ETC |
Electric transport chain |
FADH2
|
flavin adenine dinucleotide |
FBXO7 |
F-box only protein 7 |
GLP-1RA |
glucagon-like peptide-1 |
GPX |
glutathione peroxidase |
GSH |
Glutathione |
HO• |
hydroxy radical |
IMS |
Intermembrane space |
LRRK2 |
Leucine rich repeat kinase 2 |
MELAS |
mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes syndrome |
Mfn-1 and 2 |
Mitofusins 1 and 2 |
MIM |
Mitochondrial inner membrane |
ΔΨm |
Mitochondrial membrane potential |
MOM |
Mitochondrial outer membrane |
MOMP |
Mitochondrial outer membrane permeabilization |
MPTP |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
mtDNA |
Mitochondrial DNA |
mTOR/mTORC1 |
Mammalian target of rapamycin/mammalian target of rapamycin complex I |
nDNA |
Nucleus DNA |
NADH |
nicotinamide adenine dinucleotide |
NF-κB |
Nuclear factor kappa-light-chain-enhancer of activated B cells |
NOX |
Nicotinamide adenine dinucleotide phosphate oxidase |
Nrf2 |
nuclear factor erythroid 2–related factor 2 |
OPA1 |
optic atrophy 1 |
OXPHOS |
Oxidative phosphorylation |
PD |
Parkinson disease |
PGC |
Peroxisome proliferator-activated receptors (PPAR) γ coactivator |
PINK1 |
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 |
PPAR |
Peroxisome proliferator-activated receptor |
ROS |
Reactive oxygen species |
rRNA |
Ribosomal rna |
SGLT2 |
sodium–glucose cotransporter 2 |
SOD |
Superoxide dismutase |
SIRT-1 |
Sirtuin-1 |
TCA |
Tricarboxylic acid |
TNF-α |
tumor necrosis factor α |
TRX |
Thioredoxin |