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. 2021 Dec 30;14(1):180. doi: 10.3390/cancers14010180

Table 2.

Polled analysis of patient characteristics among included trials.

Outcome No. of Studies Events/Participants
or Mean ± SD
Events Heterogeneity
between Trials
p-Value for
Differences
across Groups
Robotic Laparoscopic OR
or MD
95%CI p-Value I2
Statistic
Sex, male 39 2564/3858
(66.5%)
3345/5408
(61.9%)
1.16 1.05 to 1.28 0.32 9% 0.003
Age 37 60.0 ± 16.1 62.2 ± 12.7 −0.91 −1.79 to 0.02 <0.001 70% 0.04
BMI 31 25.1 ± 4.9 24.6 ± 4.3 0.14 −0.22 to 0.49 <0.001 78% 0.45
ASA score
1 class 27 603/2358
(25.6%)
884/3628
(24.4%)
0.97 0.84 to 1.12 0.45 0% 0.70
2 class 27 1333/2358
(56.5%)
1878/3628
(51.8%)
1.19 0.99 to 1.44 0.001 51% 0.07
3 class 27 385/2358
(16.3%)
735/3628
(20.3%)
0.84 0.68 to 1.04 0.08 30% 0.11
4 class 27 13/2358
(1.6%)
36/3628
(3.5%)
0.90 0.44 to 1.83 0.83 0% 0.77
Neoadjuvant therapy 21 1000/2046
(48.9%)
1347/3541
(38.0%)
1.67 1.34 to 2.09 0.001 55% <0.001
Tumour distance from AV (cm) 18 7.4 ± 3.5 8.5 ± 3.4 −0.72 −1.17 to −0.26 <0.001 79% 0.002
Tumour location
Upper rectum 10 203/1385
(14.7%)
476/2867
(16.6%)
0.61 0.44 to 0.83 0.02 56% 0.002
Middle 10 631/1385
(45.6%)
1254/2867
(43.7%)
1.11 0.93 to 1.32 0.21 25% 0.24
Lower 14 800/1919
(41.7%)
1334/3457
(38.6%)
1.18 0.92 to 1.52 <0.001 71% 0.18

Legend: BMI = Body Mass index; CI: confidence interval; MD = mean difference; OR = odds ratio; SD = standard deviation. Note: Not all outcomes were reported in every study. “No. of studies” refers to the studies included in the analysis for the particular outcome.